Categoria: Paper

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer’s Disease Models

di ciro_isidoro

Rosa Resende  1   2 , Marisa Ferreira-Marques  1   3 , Patrícia Moreira  1   3 , Judite R M Coimbra  1   4 , Salete J Baptista  1   5 , Ciro Isidoro  6 , Jorge A R Salvador  1   4 , Teresa C P Dinis  1   7 , Cláudia F Pereira  1   8 , Armanda E Santos  1…

Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets

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Rohini Gomathinayagam  1 , Ji Hee Ha  1 , Muralidharan Jayaraman  1 , Yong Sang Song  2 , Ciro Isidoro  3 , Danny N Dhanasekaran  1     Affiliations 1 Stephenson Cancer Center, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. 2 Department of Obstetrics and Gynecology, Cancer Research Institute, College of Medicine,…

Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome

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Reza Salehi  1 , Hannah L Mazier  1   2 , Anne-Laure Nivet  1   2 , Arkadiy A Reunov  3 , Patricia Lima  1 , Qi Wang  1 , Arianna Fiocco  2   4 , Ciro Isidoro  5 , Benjamin K Tsang  6   7   Affiliations 1 Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Canada. 2 Department of Cellular &…

Nutraceuticals and diet in human health and disease. The special issue at a glance

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Ciro Isidoro  1   Affiliation 1 Università Del Piemonte Orientale, Department of Health Sciences, Novara, Italy.   PMID: 32670811 PMCID: PMC7340978 DOI: 10.1016/j.jtcme.2020.06.002 Editorial J Tradit Complement Med. 2020 Jul 6;10(3):175-179. doi: 10.1016/j.jtcme.2020.06.002. eCollection 2020 May.   Abstract This first Special Issue collects fifteen original research and up-to-date review articles addressing the beneficial properties of…

The antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds – Additional weapons in the fight against the COVID-19 pandemic?

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Andréa D Fuzimoto  1 , Ciro Isidoro  2   Affiliations 1 Holistic Sync – Holistic Integrative Medicine, USA/Brazil. 2 Dipartimento di Scienze della Salute, Università “A. Avogadro”, Novara, Italy.   PMID: 32691005 PMCID: PMC7260130 DOI: 10.1016/j.jtcme.2020.05.003   Review: J Tradit Complement Med. 2020 May 30;10(4):405-419. doi:  10.1016/j.jtcme.2020.05.003. eCollection 2020 Jul.   Abstract Introduction: As of March…

Differential effects of thymoquinone on lysophosphatidic acid-induced oncogenic pathways in ovarian cancer cells

di ciro_isidoro

Ji Hee Ha  1   2 , Muralidharan Jayaraman  1   2 , Rangasudhagar Radhakrishnan  1 , Rohini Gomathinayagam  1   2 , Mingda Yan  1 , Yong Sang Song  3 , Ciro Isidoro  4 , Danny N Dhanasekaran  1   2   Affiliations 1 Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73104, USA. 2 Department…

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